Calcinosis cutis associated with primary Sjogren's syndrome: strong expression of osteonectin and matrix Gla protein

Massive calcinosis cutis associated with primary Sjögren's syndrome.

To cite: Tsuchida Y, Sumitomo S, Fujio K, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-214006 DESCRIPTION A 28-year-old Japanese woman presented with subcutaneous nodules on the extensor surface of her elbows and knees, which had been present for 6 years. Radiographs of the knees showed numerous calcifications, up to 13 mm in diameter, in the subcu...

Calcinosis Cutis in CREST Syndrome

Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin and classified as metastatic, dystrophic, idiopathic and iatrogenic. The present case has calcinosis cutis with features of Raynaud’s phenomenon, oesophageal dysmotility, sclerodactyly and telangiectasia (CREST syndrome) the patients with CREST syndrome often have better prognosis than di...

Calcinosis cutis.

1 of 2 DESCRIPTION An 87-year-old woman with a history of hypertension, atrial fi brillation, and mixed connective tissue disease was admitted to hospital because of heart failure. Besides clinical signs of ventricular dysfunction, physical examination showed painless, subcutaneous nodules that had developed during the past 10 years on her left elbow ( fi gure 1A ) and knees ( fi gure 1B , righ...

Calcinosis Cutis

Evaluation of gene expression pattern of matrix gla protein and Bone gla protein as skeletogenesis markers in Persian sturgeon (Acipenser persicus Bordin, 1897)

Bone gla protein and matrix gla protein are of common origin with evolutionary relation and have similar structural features and are functional in the formation of skeletal structures The present study have been evaluated the genes encoding vitamin k-dependant proteins (VKDPs) expression at hatching time (0), 1, 3, 6, 10, 12,14, 20, 30 and 50 in skeletal Persian sturgeon sturgeon (Acipenser per...